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GLP-1 Semaglutide Rx
Comparison matrix
CapturedNexLife$110semaglutide · captured 2026-08-03Trimi$125tirzepatide · captured 2026-07-27Fifty 410$133tirzepatide · captured 2026-07-27NexLife$147tirzepatide · captured 2026-08-03Mochi Health$178semaglutide · captured 2026-08-03Mochi Health$278tirzepatide · captured 2026-08-03LillyDirect$299tirzepatide · captured 2026-07-27CapturedNexLife$110semaglutide · captured 2026-08-03Trimi$125tirzepatide · captured 2026-07-27Fifty 410$133tirzepatide · captured 2026-07-27NexLife$147tirzepatide · captured 2026-08-03Mochi Health$178semaglutide · captured 2026-08-03Mochi Health$278tirzepatide · captured 2026-08-03LillyDirect$299tirzepatide · captured 2026-07-27
Prices 35 verified of 82 Rubric v1.0-draft Captured today 26 Evidence records 109 verified Corrections open log

Tool

This figure has a stated end date

The $149 rate on this page is not open-ended. The $149 rate covers 1.5 mg and 4 mg. The 4 mg price rises to $199 after this date. It stops applying on 2026-08-31, in 28 days.

We flag it because a price with a known expiry that is published without one becomes a wrong price on a specific, predictable date — which is the failure this publication documents in others. Every figure with a stated end date carries a valid_until field in our open export.

GLP-1 Total Cost Calculator

All calculations show inputs, formula, date and disclaimer

Direct answer

This tool calculates from the figures you enter and publishes its formula and assumptions below the result. It stores nothing, sends nothing, and collects no health information. It does not recommend a medication, a dose, a provider or a course of treatment.

Answer last reviewed: not yet reviewed
What you are charged

Some providers charge more at higher doses. Enter the surcharge at the dose you expect to be on.

Where your money goes, from the figures you entered
MedicationMembershipShippingDose surchargeConsultationLabsStructure only. No widths are proportional to anything, because nothing is captured.
Show this figure as a table
Data table
ComponentAmount
Medicationnot captured
Membershipnot captured
Shippingnot captured
Dose surchargenot captured
Consultationnot captured
Labsnot captured
All-in totalnot captured
A provider that advertises only the first segment is quoting a price you cannot actually pay.
Projected total by term
6 monthsnot captured12 monthsnot captured24 monthsnot captured
Show this figure as a table
Data table
ItemValueEvidence
6 monthsnot captured
12 monthsnot captured
24 monthsnot captured
Projection updates live from the fields above once you enter figures.
Assumptions behind this calculation
Data table
Recurring costsMedication, membership, shipping and dose surcharge are multiplied by the number of months.
One-off costsConsultation and laboratory fees are added once. If your provider bills them repeatedly, enter them as a monthly cost instead.
Dose escalationNot assumed. Enter the surcharge for the dose you expect to reach.
InsuranceNot modelled. This is a self-pay calculation.
RoundingDisplayed to the nearest dollar; the calculation is not rounded.

Why an all-in figure is the only comparable one

Providers in this category publish a monthly medication price. Almost none publish what you will actually pay, because between the advertised figure and the amount leaving your account sit up to five other charges: a membership, shipping, an initial consultation, required laboratory work and a surcharge that applies once you titrate above the starting dose.

Each is disclosed somewhere. None is usually in the headline. The result is that a straight comparison of advertised prices ranks providers in an order that does not survive contact with a bank statement.

The formula, in full

(medication + membership + shipping + dose surcharge) × months + consultation + labs

Recurring costs multiply by the term. Consultation and laboratory fees are treated as one-off, because most providers charge them at intake — if yours bills them repeatedly, enter them as monthly costs instead and the projection will follow.

Two things the calculator deliberately does not assume

It does not assume a dose. If your provider charges more at higher doses, enter the surcharge for the dose you expect to reach rather than the one you start on. The label schedule runs 2.5 mg for four weeks and then upward; the starting dose is a tolerance dose and is not where you will spend your treatment.

It does not assume you stop. The projection runs to 36 months because the withdrawal evidence suggests treatment continues to hold its result. In SURMOUNT-4, participants withdrawn after a lead-in regained 14% of body weight over the following year while those continuing lost a further 5.5%. That is the argument for comparing indefinite monthly cost rather than a first-year total.

What to do with the result

Run it twice: once with the figures a provider advertises, and once with the figures they confirm in writing at a maintenance dose. The gap between those two numbers is the most useful thing this tool produces.

Cite this pageCC BY 4.0

GLP-1 Semaglutide Rx. “GLP-1 Total Cost Calculator.” S.J Partners LLC, 2026-08-03. https://glp1semaglutiderx.com/tools/glp1-cost-calculator/

Quote the capture date beside a figure, not the date you read this page. Why.

What each route costs a month, and over a year
RouteMonthlyTwelve monthsEvidence
Covered brand plus savings card$25$300Provider-reported
Medicare GLP-1 Bridge$50$600Reported
Approved oral GLP-1$149$1,788Captured at source
Compounded tirzepatide, flat, 12-month$186$2,232Captured at source
Brand Zepbound, LillyDirect vials$299–$449$4,788Captured at source
Brand Zepbound, retail pens~$1,060~$12,720Third-party claim

Prices re-confirmed at source on 2026-08-03. The compounded row has no trial of its own; every efficacy figure on this site was collected on the approved product. Full ladder and evidence grades: the ranking.

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