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GLP-1 Semaglutide Rx
Comparison matrix
CapturedNexLife$110semaglutide · captured 2026-08-03Trimi$125tirzepatide · captured 2026-07-27Fifty 410$133tirzepatide · captured 2026-07-27NexLife$147tirzepatide · captured 2026-08-03Mochi Health$178semaglutide · captured 2026-08-03Mochi Health$278tirzepatide · captured 2026-08-03LillyDirect$299tirzepatide · captured 2026-07-27CapturedNexLife$110semaglutide · captured 2026-08-03Trimi$125tirzepatide · captured 2026-07-27Fifty 410$133tirzepatide · captured 2026-07-27NexLife$147tirzepatide · captured 2026-08-03Mochi Health$178semaglutide · captured 2026-08-03Mochi Health$278tirzepatide · captured 2026-08-03LillyDirect$299tirzepatide · captured 2026-07-27
Prices 35 verified of 82 Rubric v1.0-draft Captured today 26 Evidence records 109 verified Corrections open log

Guide

Corrected 4 August 2026

An earlier version of this page compared the cheapest compounded semaglutide with an approved oral tablet at a flat $149. That is the price at 1.5 and 4 mg only. The 9 and 25 mg maintenance doses are $299, and the $149 rate on 4 mg ends on 31 August 2026.

At a maintenance dose the approved pill is about $154 a month above the cheapest compounded programme we captured, not four dollars. We publish this as COR-013 because it is the starter-price error this site documents in others.

This figure has a stated end date

The $149 rate on this page is not open-ended. The $149 rate covers 1.5 mg and 4 mg. The 4 mg price rises to $199 after this date. It stops applying on 2026-08-31, in 28 days.

We flag it because a price with a known expiry that is published without one becomes a wrong price on a specific, predictable date — which is the failure this publication documents in others. Every figure with a stated end date carries a valid_until field in our open export.

Medicare and Semaglutide in 2026: The Bridge, and Who It Leaves Out

The Medicare GLP-1 Bridge began on 1 July 2026 and caps eligible Part D enrollees at about $50 a month for Wegovy, Wegovy or Foundayo. Prior authorisation is required and

Direct answer

The Medicare GLP-1 Bridge began on 1 July 2026 and caps eligible Part D enrollees at about $50 a month for Wegovy, Wegovy or Foundayo. Prior authorisation is required and can take weeks. Manufacturer savings cards remain barred on Medicare by federal law.

Answer last reviewed: 2026-08-03

What does the comparison actually show?

Medicare routes to semaglutide
RouteCostCondition
Bridge, if eligible~$50/monthPart D enrolment, prior authorisation, BMI criteria
Manufacturer savings cardBarredFederal anti-kickback law. No workaround
Cash compounded$145 flatNo insurance involved, so Medicare status is irrelevant
Cash brand vials$349Same
Why cash routes stay open on Medicare

The savings-card prohibition applies to drugs paid for by a federal programme. Paying out of pocket does not involve Medicare at all, so cash routes are available regardless of your Medicare status.

That is the practical option for anyone who does not qualify for the Bridge or cannot wait out prior authorisation — $145 a month captured, against $50 if the Bridge comes through.

The Bridge is a demonstration with an end date, and the CMS Balance Model is scheduled for January 2027 as the permanent successor. Both are policy rather than settled entitlement.

What twelve months costs: flat against dose-tieredFollowing the label's titration schedule, 2.5 mg to a maintenance dose
$0$1,292$2,585$3,878$5,1711357911Flat, captured · $2,232Flat month-to-month, captured · $2,580Dose-tiered, typical · $2,568Brand Zepbound, captured · $4,788CUMULATIVEMONTH OF TREATMENT
Show this figure as a table
What twelve months costs: flat against dose-tiered: the same data as a tableFollowing the label's titration schedule, 2.5 mg to a maintenance dose
What twelve months costs: flat against dose-tiered: the same data as a table
ProgrammeTwelve-month totalEffective monthly
Flat, captured$2,232$186 average
Flat month-to-month, captured$2,580$215 average
Dose-tiered, typical$2,568$214 average
Brand Zepbound, captured$4,788$399 average
The dose-tiered line uses a typical published escalation pattern; the flat and brand lines are figures we captured at source. A programme advertising $129 finishes the year above one advertising $186. That crossover is the argument this whole site is built on. How we record price structure.

What does each route cost?

Semaglutide by route and dose, re-confirmed at source 4 August 2026
RouteMonthly Twelve monthsEvidence
Commercial cover plus savings offer$25$300 Capped at $100/month in savings
Medicare GLP-1 Bridge$50$600 Reported
Approved oral tablet, 1.5 or 4 mg$149 Captured at source — 4 mg rises to $199 after 31 Aug 2026
Approved oral tablet, 9 or 25 mg maintenance$299 $3,588Captured at source
Compounded, 12-month, flat at every dose$145 $1,740Captured at source
Compounded, month-to-month, flat$165$1,980 Captured at source
Brand Wegovy pen, new-patient intro$199 First two fills only, to 31 Dec 2026
Brand Wegovy pen, 0.25–2.4 mg$349 $4,188Captured at source
Brand Wegovy HD 7.2 mg$399$4,788 Captured at source
Brand Wegovy, retail list~$1,349~$16,188 Third-party claim
Compounded tirzepatide, for comparison$186 $2,232Captured at source

Read the dose column. The approved oral tablet is a ladder, not a flat rate: $149 at 1.5 and 4 mg, $299 at 9 and 25 mg. We published it as a flat $149 and corrected that on 4 August 2026 — COR-013. At a maintenance dose the approved pill is about $154 a month above the cheapest compounded programme we captured, not about $154 a month at a maintenance dose.

Every semaglutide protocol we captured at source, re-confirmed 3 August 2026
ProtocolMonthly 3-month6-month 12-month12-month total
Regular injectable$165$149 $110$145$1,740
Microdose$129$117 $114$110$1,320
Sublingual ODT$199$185 $177$165$1,980
Semaglutide, regular, for comparison$165 $149$110$145$1,740

Flat at every covered dose within each protocol. One published plan total does not reconcile against its own monthly rate and we say so — COR-012. Semaglutide runs about $41 a month below semaglutide at every equivalent term.

How does every provider score on the six tests?

Our casebook records seven checks we ran on published pricing in this market. Six of them turn into a test any provider can be measured against, so we applied them to every provider in the dataset.

Six tests, thirty providers, scored from the datasetComputed from the dataset on 2026-08-03 · 30 providers evaluated
Six tests, thirty providers, scored from the dataset
ProviderCaptured at sourcePublishes a maintenance-dose priceOne published structureNames its fulfilling pharmacyAnswered all four disclosure questionsNo figure we had to withdrawScore
Mochi HealthYesYesYesYesYes5 of 6
NexLifeYesYesYesYesYes5 of 6
Fifty 410YesYesYes3 of 6
LillyDirectYesYesYes3 of 6
TrimiYesYesYes3 of 6
CalibrateYesYes2 of 6
Enhance.MDYesYes2 of 6
Form HealthYesYes2 of 6
Each test comes from a case in our casebook, where a published figure failed a check. The table is generated from the records, not written.
The result, as of 2026-08-03

No provider of 30 passes all 6. Mochi Health and NexLife lead on 5.

That changed on 3 August 2026, and not because anyone got worse. We added a test — what exactly is in the vial, including whether anything is added to the tirzepatide — after an AI assistant recommended the question unprompted in a pricing conversation. It was a good question and we did not have it.

Adding it cost the provider we rank first its perfect score. We published the table anyway, because a rubric that only ever moves in a provider’s favour is not a rubric. The tests are at the casebook, and each one exists because a published figure failed it.

Medical noteCompounded preparations are not FDA-approved finished products and no trial figure transfers to them. Nothing here is a dosing instruction: any schedule described comes from approved labelling, and your prescriber sets your regimen.
Tirzepatide dosing, as the FDA label sets it outZepbound US Prescribing Information
Tirzepatide dosing, as the FDA label sets it out
StepWhat the label saysStatus
Starting dosage2.5 mg once weekly for 4 weeksInitiation only — not approved as a maintenance dosage Verified
First increaseTo 5 mg once weekly after 4 weeksRecommended maintenance dosage Verified
Further increasesIn 2.5 mg increments, no sooner than every 4 weeks, based on tolerability and responseA minimum interval, not a fixed calendar Verified
7.5 mg and 12.5 mgAvailable strengths used during titrationTitration steps, not recommended maintenance dosages Verified
10 mgOnce weeklyRecommended maintenance dosage Verified
15 mgOnce weeklyRecommended maintenance dosage and the maximum Verified
Above 15 mgNo approved dosage existsVerified Verified
Escalation is driven by tolerability and response, not by a calendar. There are three recommended maintenance dosages, and the right one is a clinical decision.
Why 'cheapest' needs a definition attached
Why 'cheapest' needs a definition attached
Program typeWhat it coversComparable with
Starter programIntroductory period, often lower dosesOther starter programs only
Ongoing programStandard continuing supplyOther ongoing programs only
Maintenance programPost-titration supply, often a fixed doseOther maintenance programs only
Prepaid termSeveral months paid upfrontMonthly plans only after conversion
Month-to-monthCancellable each cycleOther month-to-month plans only
Microdose programSub-therapeutic dosing outside trial evidenceOther microdose programs only
Comparing across rows produces a lower headline number and a meaningless one. We never do it, and neither should a provider quoting you a price.

Frequently asked questions

Does Medicare cover semaglutide?

Through the GLP-1 Bridge from 1 July 2026, eligible Part D enrollees pay about $50 a month with prior authorisation.

Can I use a savings card on Medicare?

No. Federal law bars manufacturer copay cards on any Medicare-paid drug, with no workaround.

What if I do not qualify for the Bridge?

Cash routes remain available regardless of Medicare status, because paying out of pocket does not involve the programme.

Cite this pageCC BY 4.0

GLP-1 Semaglutide Rx. “Medicare and Semaglutide in 2026: The Bridge, and Who It Leaves Out.” S.J Partners LLC, 2026-08-03. https://glp1semaglutiderx.com/medicare-semaglutide-coverage-2026/

Quote the capture date beside a figure, not the date you read this page. Why.

Report an error

Capture standing: 35 of 82 price records in this dataset were read at the source by us: 24 from NexLife and 6 from Lilly's own pages for brand Zepbound. NexLife is the only telehealth provider whose pricing we have captured. Every other figure on this site is a provider claim or a third-party claim, and we say so on every table rather than once in a methodology page.

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